Renal amyloidosis

Kidney amyloidosis is a chronic disease characterized by accumulation of abnormal proteins - amyloid kidney.

Etiology

Renal amyloidosis occurs secondary to the disease such as tuberculosis, chronic suppuration, tumors and rheumatoid arthritis.

The clinical picture

Amyloidosis primary surgery glomeruli, a major clinical findings were proteinuria (protein in urine findings). In the beginning was to moderate and intermittent proteinuria, but becomes more pronounced over time, developed nephrotic syndrome and renal failure. Amyloid is deposited first in the mesangium, and in the tubules leading to renal tubular acidosis.

Diagnosis

It is based on renal biopsy and histopathological examination of the sample obtained, or evidence of amyloid in submucosal lining of the rectum.

Treatment

Treatment of the underlying disease can lead to partial regression of renal changes.Treating the nephrotic syndrome. Dimethylsulfoxide is used in amyloidosis caused by rheumatoid arthritis - leading to the recovery of renal function. The terminal uremia apply to dialysis and kidney transplantation.

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